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Eubios News in Bioethics & Biotechnology - March 2003

Eubios Journal of Asian and International Bioethics 13 (2003), 65-73.

Comments are written in text form together with recent references. This list continues from the last issue of EJAIBand will continue. The full list of news (OLD = 1991-1993; NEW = 1994+) is available on-line topic-by-topic, at: http://eubios.info/NBB.html

Abbreviations


News in Bioethics & Biotechnology

Comments are written in text form together with recent references. This list continues from the last issue of EJAIB and will continue. This list is available on-line topic-by-topic, at:
http://eubios.info/NBB.html


Genetic Engineering of Plants

Organic farming and FAO is discussed in J. Biolaw & Biobusiness Special Supplement (2000), 125-6; among a series of papers on biotechnology in agriculture, pp. 3-128. Directions and challenges of agricultural technology  in 2010 is discussed in Technology in Society 23 (2001), 59-72. Since the 1940s the changing climates may have been a major cause of increased agricultural yields, Science 299 (2003), 997. Study of New World plant domestification are discussed in Science 299 (2003), 1029-30. Hominid land use 1-2 million years ago is discussed in Science 299 (2003), 1217-21.

The future of bananas, which are being subject to many diseases, are reviewed in NS (18 Jan., 2003), 26-9. However genetically modified bananas can find nematode pests, NS (1 Feb., 2003), 15. GM cotton is allowing more conservation tillage, AgraFood Biotech. 97 (3 Feb. 2003), 15. Science and food security in Africa is discussed in Science 299 (2003), 1187-8; and on food security in Brazil, Lancet 361 (2003), 586. On the replacement of older methods of breeding by GM, Nature 421 (2003), 568-70.

The complete rice genome sequence is on the Internet for free access, NS (11 Jan., 2003), 5. Iron fortified rice was chosen as the 1st milestone of 2003 by researchers in a survey, NS (4 Jan., 2003), 24-5. India is planning a protato as a GM potato to alleviate hunger, NS (4 Jan., 2003), 7; Ram's Horn 208 (Jan. 2003), 6-7. Risks of GM trees to forests were assessed in a field trial, NS (25 Jan., 2003), 8. GM wine is discussed in NS (21 Dec. 2002), 33-5.

 

Genetic Engineering of Animals

The death of Dolly, the first mammalian clone, at 6 years of age has been widely reported, Lancet 361 (2003), 711; Nature 421 (2003), 776; Int. Herald Tribune (15 Feb. 2003). New Zealand scientists have announced GM cows with enhanced milk protein levels, NatBio (Feb. 2003); NS (1 Feb. 2003), 6. A report on pig cloning from China is Cloning 2 (2002), 45+. Production of alpha 1,3-galactosyltransferase deficient pigs is reported in Science 299 (2003), 411-4. Japanese researchers have cloned a monkey, APBN 7 (2003),  6-7. Controversy over cloning prized cattle livestock in the USA is discussed in Current Biology 12 (2002), R828. A review of reproductive technologies in domestic animals is Cloning 1 (1999), 133-42. Genetic engineering of livestock is reviewed in J. Biolaw & Biobusiness Special Supplement (2000), 29-33, 38-41.

In general on mouse models of disease, The Scientist (13 Jan. 2003), 35;  Science 298 (2002), 2320-1. Mice lacking insulin receptor in adipose tissue live longer,  Science 299 (2003), 572-4. Circulating platelets exacerbate atherosclerosis in apolipoprotein E deficient mice models, NatMed. 9 (2003), 61-6. Spongiform degeneration in mahoganoid mutant mice is described in  Science 299 (2003), 710-3. Mice follow olfactory response in social network building,  Science 299 (2003), 1163. NCF1 is a gene regulating arthritis severity in rats, NatGen 33 (2003), 25+. Longevity is discussed in Nature 421 (2003), 125-6. Inactivation of genes using RNA in nematode worms has been reported for study, Nature 421 (2003), 220-1, 231-7, 268-72; NatGen 33 (2003), 40-7. Fruit flies as models for neuropharmacological research are discussed in Trendsin Pharmaceutical Sciences 24 (2003), 41-3. Myc-induced leukemia in transgenic zebrafish is reported in  Science 299 (2003), 88-90.

 

Designer Molecules

Transgenic silkworms can spin human collagen into cocoons, Lancet 360 (2002), 2053. Design and synthesis of a protein using chemistry is reported in  Science 299 (2003), 884-7. The first autonomous synthetic lifeform has been made,  Science 299 (2003), 640; J. American Chemical Society (31 Jan 2003). Biomaterials in sensors are reviewed in  Science 298 (2002), 2407-8. Nanotechnology is using some biological molecules,  Science 298 (2002), 2322-3; 293 (2003),  1192-3. Protein networking is discussed in  Science 299 (2003), 1159. Damaged RNA can be repaired by cells, Nature 421 (2003), 795-6.

 

Biotechnology  &  the Public

Public understanding of genetics is discussed in New Genetics and Society 21 (2002), 315-26. The media discourse over the genome project is reviewed in New Genetics and Society 21 (2002), 327-38. Papers on biotechnology and the public include: J. Biolaw & Biobusiness Special Supplement (2000),  107-10, 120-4. On the ethics of biotechnology,  Technology in Society 23 (2001), 241-64; J. Biolaw & Biobusiness Special Supplement (2000), 111-5. A book review of Fukuyama, F., Our Posthuman Future is JAMA 289(2003), 488-90.

Papers on risks of genetic engineering include Medicine, Health Care and Philosophy 1 (1998), 61-4. A series of papers on the 25th anniversary of the Asilomar Conference are in Perspectives in Biology and Medicine 44 (Spring 2001), 159-247. Papers on the 50th anniversary of the paper on DNA structure are in Nature 421 (2003), 310-2, Nature Special Supplement The double helix - 50 years, pp. 396-450. Book reviews of Watson and DNA are in Nature 421 (2003), 315-6; and on Rosalind Franklin, BMJ 326 (2003), 289. Perceptions of science are affected by the portraits of scientists,  Science 299 (2003), 831-2.

The importance of medical knowledge for health is made in Lancet 361 (2003), 716. Communicating health risks is discussed in Medicine, Health Care and Philosophy 3 (2000), 239-40, 241-9; NEJM 348 (2003), 88-9. The space shuttle Columbia breakup reveals the risks of space travel, Nature 421 (2003), 559.

Religion and science in USA is discussed in  Science 299 (2003), 664; SA (Feb. 2003), 15. Spirituality affects health care, BMJ 326 (2003), 1434-5; AJPH 93 (2003), 185.  Politics and science is discussed in  Science 299 (2003), 625, 977. The interface between security and science is discussed in  Science 299 (2003), 1148.

 

Regulation & Field Trials of GMOs

The Philippines has allowed Bt corn planting for commercial purposes, APBN 7 (2003), 14. Uganda is encouraging more research into GM crops, Lancet 361 (2003), 500. A book review of genes for Africa is Nature 421 (2003), 478-9. Chinese are showing more cautious attitudes towards GM crops,  Science 298 (2002), 2317-8; 299 (2003), 1013. The results of Indian GM cotton harvest are discussed in Nature 421 (2003), 681. Poor farmers have been warned against making deals for GMOs over the Internet, Nature 421 (2003), 776. 12 GMOs have been registered for growth in Russia, AgraFood Biotech 95 (9 Dec. 2002), 6. There is some concern in Japan over the unclear biotechnology regulations, Nature 421 (2003), 689.

There may be a further 18 months before transgenic salmon are approved for commercial farming in the USA, Nature 421 (2003), 304. European responses to biotechnology regulation are discussed in Issues in Science and Technology (Summer 2001), 37-42. The European Commission has told EU governments to stop delaying new GM reviews, Financial Times (4 Feb. 2003). French experts on GMOs have been subject to threats and slander from protest groups, Nature 421 (2003), 775. Education in biosafety is needed for the public also,   Science 299 (2003), 25. On GMOs in Australasia and rabbit control, NS (4 Jan. 2003), 29. In general on GMO risks, Nature 421 (2003), 675.

A study of GM mosquitoes is Catteruccia, F. et al. "Impact of genetic manipulation on the fitness of Anopheles stephensi mosquitoes",  Science 299 (2003), 125-7. Trials of gene transfer suggest weeds that receive genes from GMOs are not strong, Nature 421 (2003), 462. GM sugarbeet in the UK seem to be good for wildlife, NS (18 Jan. 2003), 6. Design of biosafety labs is discussed in  Science 299 (2003), 812-5.

The precaution necessary to handle possible life from other plants is discussed in Discover 24 (March 2003), 60-5.

Challenges of biowarfare are discussed in Meslin, EM. "Bioterrorism and bioethics: Challenges for industry, government and society", J. Commercial Biotechnology 9 (2003), 101-10; Nature 421 (2003), 787. Preparation for biological and chemical weapon attacks is discussed in Lancet 361 (2003), 786-7; Nature 421 (2003), 564. The statement on the consideration of biodefence and biosecurity reached by a number of editors is in Nature 421 (2003), 771. Tighter controls on biological research have appeared in the USA, Science 298 (2002), 2304; NS (18 Jan. 2003), 10. There is debate over smallpox vaccination plans, and over interpreting old data,  Science 298 (2002), 2312-6; 299 (2003), 181, 486-7; BMJ 326 (2003), 179; NEJM 348 (2003), 426-32, 460-6. Fears of agroterrorism, The Scientist (13 Jan. 2003), 54; Nature 421 (2003), 106-8.

 

Vaccines & Diseases

Survey of the publications of medical journals has found a bias against papers on diseases of poverty, Lancet 361 (2003), 712-3. Bill Gates has announced a further US$200 million fund to combat diseases of the poor, Lancet 361 (2003), 404; Science 299 (2003), 641. See comments also in Lancet 360 (2002), 1617. Global Fund pledges are discussed in Lancet 359 (2002), 435-8, 499, 1581-2; 360 (2002),  1225. On poor disease markets, NatMed. 9 (2003), 7. Novartis has set up an Institute for Neglected Diseases, Science 299 (2003), 811. Parasite control at schools may be introduced in Africa, Lancet 361 (2003), 497. Papers on the burden of disease include:  JAMA 289 (2003), 621-2; J. Public Health Policy 22 (2001), 5-97; NatMed. 9 (2003), 11; Lancet 360 (2002),1342, 1347-60. A study of the diseases which cause differences in longevity between races is in NEJM 347 (2002), 1585-92; Lancet 360 (2002), 1571.

A NOS2 promoter polymorphism may be associated with malaria protection, Lancet 360 (2002), 1468-75. Malaria research is discussed in Science 298 (2002), 79-86; 299 (2003), 705-8; Nature 415 (2002), 669-715; 419 (2002), 426-431; 420 (2002), 345; 421 (2003), 97, 461; JAMA 289 (2003), 619; Lancet 360 (2002), 1075, 1107; NatMed. 8 (2002), 104. Insect repellents for mosquitoes are discussed in NEJM 347 (2002), 1719-21. Climate change leads to increased malaria, Nature 415 (2002), 905-8.

Vaccine safety is discussed in Madsen, KM. Et al. "A population-based study of measles, mumps, and rubella vaccination and autism", NEJM 347 (2002), 1477-82; JAMA 287 (2002), 1455-62; 288 (2002), 3155-8; BMJ 324 (2002), 733-5, 383; 325 (2002), 430-3, 597, 603; Lancet 359 (2002), ,2051-2; NS (16 Feb 2002), 5. Vaccination against Haemophilus influenzae type b may need to be increased as the number of cases in the UK increases, Lancet 361 (2003), 395-6. Hepatitis B vaccination may need to be repeated in late teens, BMJ 325 (2002), 569-72.  Nigerian immunization has reduced disease, BMJ 326 (2003), 121. Vaccine uptake is discussed in Lancet 360 (2002),  1596-9. Research into why some people are resistant to disease is discussed in NS (8 Feb., 2003), 34-7; NatGen 32 (2002), 97-105. Mortality from influenza is discussed in JAMA 289 (2003), 179-86, 227-89; NEJM 347 (2002), 2159-61. DNA vaccine trials include NatMed. 9 (2003), 33-9.

A polio outbreak in India has delayed global eradication plans, NS (5 Oct. 2002), 8. The role of monkey virus SV40 in old polio vaccines in cancer is unclear, Lancet 359 (2002), 812, 817-23; 360 (2002), 1307. A review of dengue vaccines is Lancet 360 (2002), 1243-5. A Human paillomavirus type 16 vaccine trial was reported in NEJM 347 (2002), 1645-51. Edible vaccines are discussed in NatMed. 8 (2002), 94.

There has been debate over the US smallpox vaccination campaigns regarding safety and compensation for injuries, BMJ 326 (2003), 179; NEJM 348 (2003), 416-25.

The genome sequence of Vibrio parahaemolyticus has revealed a different pathogenic mechanism to cholera, Lancet 361 (2003), 743-9. The genetics of the bacterium Tropheryma whipplei that causes Whipple disease is revealed after genome sequencing in Lancet 361 (2003), 632, 637-44. A new test for plague has been released, Lancet 361 (2003), 191, 211-6.

Iron Age TB has been detected in the UK, Science 299 (2003), 341. Immunotherapy for TB is discussed in Lancet 360 (2002), 1032-3. On TB control, NEJM 347 (2002), 1420-5, 1444. Study of Bdellovibrio , the fastest bacterium, is discussed in Wellcome News (Q4, 2002), 26. On bacterial meningitis in Africa, Lancet 360 (2002), 2054. Antibacterial proteins in calf saliva may be added to toothpaste, NS (11 Jan., 2003), 14. West Nile virus in USA is discussed in NatMed. 9 (2003), 1051. The chances of a couple having the same disease are reported in BMJ 325 (2002), 636-8. Exposure to endotoxin is important in development of asthma, NEJM 347 (2002), 869-77. On the hygiene hypothesis, NEJM 348 (2003), 930-1.

Genetic susceptibility to variant CJD is discussed in Lancet 361 (2003), 447-8, 487-9, 531-2. In 2002 17 people died from CJD in the UK, less than 20 in 2001 and 28 in 2000, Lancet 361 (2003), 751-2; Science 295 (2002), 332-5. Japan has announced a total of 7 cases of variant CJD from BSE. On Japanese CJD, Lancet 359 (2002),  1219; Newsweek (25 March 2002), 26-7. Therapy for CJD may be possible, BMJ 326 (2003), 8; NS (26 Oct. 2002), 18. Reuse of surgical tools is one risk factor also, Lancet 360 (2002), 1485.

A survey of why UK doctors prescribe antibiotics for sore throat is BMJ 326 (2003), 138-41. Some bacteria may have lost resistance to older antibiotics, BMJ 326 (2003), 235-6. On antibiotic resistance, NEJM 347 (2002), 1213; Lancet 359 (2002), 184-5, 1791-2; NatMed. 8 (2002), 11. The structure of bacterial multidrug efflux transporter AcrB is in Nature 419 (2003), 587-93.

 

AIDS & Sexually Transmitted Diseases

HIV counseling and testing in the USA is discussed in Lancet 361 (2003), 611. Consent for HIV testing is discussed in BMJ 325 (2002), 1226-7; AJPH 92 (2002), 1931-9.  Blood banking in China is reviewed in Lancet 360 (2002), 1770-5. A review of HIV and bioethics is in Health Care Analysis 10 (2002), 5-18; also pp. 1-120. Criminalisation of HIV transmission in Scotland is discussed,BMJ 323 (2001), 1174-7.

The USA has announced it will give a further US$15 billion US towards AIDS relief in Africa and the Caribbean, Lancet 361 (2003), 539. This may overcome earlier criticism, BMJ 326 (2003), 299. Sexual behaviour in China is reported in Social Sciences in China (Winter 2002), 25-35. Also on AIDS in China, Nature 419 (2002), 99-100; BMJ 324 (2003), 803-4; and India, BMJ 324 (2002),  182-3; SSM 53 (2001), 1413-26. China is making antiretroviral drugs, BMJ 325 (2002),  1257; NatMed. 8 (2002), 649-54. Equity in drug treatment is discussed in AJPH 92 (2002), 1905-7; Lancet 360 (2002), 1503-5; JAMA 288 (2002), 841-3, 1652-3; BMJ 324 (2002), 181-2, 214-8; MJA 175 (2001), 570-2.  In the Netherlands it was found that some drugs destined for Africa were being sold in Europe, Lancet 360 (2002), 1311.

Behaviour of students in Nigeria is reported in BMJ 326 (2003), 15-8. The socio-economic impact of HIV is discussed in JAMA 289 (2003), 31-3; Lancet 360 (2002), 1. Thailand could implement its goals for preventing mother to child HIV prevention, JAMA 288 (2002), 245-8. Breast feeding and HIV is discussed in JAMA 286 (2001), 2413+, 2462-4; 287 (2002), 1110-3; Lancet 359 (2002), 855, 992; BMJ 324 (2002), 218-21. On the Japanese HIV contaminated blood trial, Lancet 359 (2002), 446.

Papers on pediatric HIV are in J. Clinical Ethics 12 (2001), 150-75. Palliative care in AIDS is discussed in J. Hospice and Palliative Nursing 3 (2001), 7-14. Ethics of HIV trials in developing countries are discussed in The Scientist (27 Jan. 2003), 22-3; NEJM 346 (2002), 1373-82; Nature 415 (2002), 365-6.

Prospects for curing HIV and AIDS are discussed in NS (8 Feb., 2003), 38-41. A phase 3 HIV vaccine trial has failed, but it may be protective in non-white participants in the trial, Lancet 361 (2003), 755-6. HIV vaccine research is discussed in NEJM 348 (2003), 643-4; NatMed. 9 (2003), 13-4, 27-32; Lancet 359 (2002), 2261-7. Prophylaxis for non-occupational HIV exposure are discussed in JAMA 289 (2003), 287-8. Individual treatment should be designed, Lancet 359 (2002), 722-3, 727+.

Genetic differences in immune response and hepatitis virus are discussed in Lancet 360 (2002), 991-5. The question of whether ticks can be a vector for hepatitis C is discussed in NEJM 348 (2003), 1724-5.

 

Microbes  & Pollution Remedies

Discussion of the advice of Spanish scientists in cleaning up the 13 November 2002 oil spill is in Science 299 (2003), 490, 511. A dioxin degrading bacterial strain of Dehalococcoides has been found in  river soil in Germany, NS (25 Jan., 2003), 21. An electrochemical system for removing mercury from a gas stream is described in EST 36 (2002), 4430-5.

 

Environmental Issues

The use of values in Environmental Decision making is discussed in Environmental Values 9 (2000), 407-530. On environmental ethics, Environmental Values 9 (2000), 125-52. Justice in environmental policy is discussed in Environmental Values 10 (2001), 5-18. On environmental policy, Science 299 (2003), 348-9. Equity is discussed in AJPH 93 (2003), 209-14; SSM 56 (2003), 573-87. Lack of progress on international environmental action is reviewed in NS (21 Dec., 2002), 18-19. On the Global Summit on sustainable development, Nature 418 (2002), 803; 420 (2002), 733. Economics is discussed in Nature 420 (2002), 123.

A call for a minimum list of pesticides for the developing world to FAO is made in Lancet 361 (2003), 259-60. Discussion of how to test for safety of pesticides is in BME 184 (Jan. 2003), 1.; NS (8 Feb., 2003), 12 Also on pesticide safety, Nature 421 (2003), 200-1; JAMA 289 (2003), 535-6; NatMed. 8 (2002), 1050. The impact of biopolymers on the environment is debated in Science 299 (2003), 822-4. A review of frog deformities is SA (Feb. 2003), 48-53. The role of environmental estrogens in deterioration of male fertility is reviewed in F&S 78 (2002), 1187-94.

Pollution causes genetic defects,  Somers, CM. Et al. "Air pollution induces heritable DNA mutations", PNAS 99 (2003), 15904-7; NS (14 Dec., 2002), 8. Mortality from traffic-related air pollution is discussed in Lancet 361 (2003), 430. On air pollution and health, Science 299 (2003), 485, 665-6; BMJ 325 (2002), 1380. Cities in Asia are suffering from smog, NS (25 Jan., 2003), 13. Ozone is one of these, EST 36 (2002), 379-82A. China is being put in the dark, NS (14 Dec., 2002), 6-7.

Consumption of arsenic from cooked rice in Bangladesh may be under-estimated, Lancet 361 (2003), 435-6. Arsenic is a maor problem there, NS (7 Dec., 2002), 9. It is also a problem in India, Nature 421 (2003), 778. Shortage of water is a global problem, SA (Jan. 2003), 78-9.  Lead burden is discussed in NEJM 348 (2003), 277-86, 345-6.  Drug pollution is discussed in Lancet 360 (2002), 1035-6.

El Nino and drought will affect many persons, Lancet 361 (2003), 437-8; Science 299 (2003), 636; NS (30 Nov., 2003), 26-9. On monsoon patterns, Nature 418 (2002), 713; 421 (2003), 324-5. Climate change may have increased US agricultural yields since the 1930s, Science 299 (2003), 1032. Carbon dioxide uptake is discussed in Science 298 (2002), 2344; 299 (2003), 235-9; Nature 421 (2003), 37-42.  The lack of US policy on climate change is criticized in Science 299 (2003), 309; NS (25 Jan., 2003), 4-5; Nature 420 (2003), 595. Litigation is one tool, SA (Feb. 2003), 8-9. Iron fertilization of the ocean is discussed in Nature 421 (2003), 109-10. Algae growth may not be a useful sink, Nature 420 (2002), 722.

Prevention of skin cancer is discussed in BMJ 326 (2003), 114-5.

Norway is using underwater coastal currents drive by tides for energy generation, Science 299 (2003), 339. Discussion of petroleum is in Science 298 (6 Dec. 2002). Conventional fuels still dominate US home heating, SA (Jan. 2003), 17. On biomass, NS (30 Nov., 2003), 8.

Chernobyl is discussed in Science 299 (2003), 44; SSM 56 (2003), 569-72. Nuclear power safety is discussed in Science 299 (2003), 201-3. Droppings from seabirds may introduce radioisotopes into the land food chain, NS (4 Jan., 2003), 5. The US has released details of the radioactivity in Nevada deserts after the tests, which reveals plutonium in ground water has moved 1.3 km through rock over 30 years, NS (8 Feb., 2003), 13. Background radiation can cause thyroid cancer, NS (11 Jan., 2003), 4.

 

Biodiversity

Fisheries management is discussed in Issues in Science and Technology (June 2001), 77-84. The Artic faces a toxic time bomb as toxins melt, NS (1 Feb., 2003), 9.  Coral reefs are being damaged by sediment, Nature 421 (2003), 317, 705-6, 727-30. A flamingo disease is discussed in NS (9 Nov., 2002), 8. Variation in Amazon forests is reported in Science 299 (2003), 241-4.  There is debate over the impact of global warming on ecology, Science 299 (2003), 38, 1165-6. However some species are known to be threatened, NS (4 Jan., 2003), 4.

The cloning of an endangered species (Bos gaurus) is described in Cloning 2 (2000), 79+. There have been ecotourism threats in New Zealand against endangered birds, NS (1 Feb., 2003), 5. On the hunt for alien life, Nature 421 (2003), 769.

 

Animal Rights

Ethics of biotechnology using animals is discussed in J. Commercial Biotechnology 9 (2003), 163-70. An Indian activist on animal rights has been removed from the government committee, BMJ 326 (2003), 68. On animal rights in general, Science 299 (2003), 1013-4.  A book review of Love at Goon Park is in NEJM 348 (2003), 670-1.

The shaping of neurons is discussed in Science 299 (2003), 32-4. Minor variation in neurotrophic growth factor impairs human memory, Science 299 (2003), 639-40. Deciphering the mind is discussed in Science 299 (2003), 496-9. Genetic variation and pain response is reported in Science 299 (2003), 1240-3.  Pheromonal mechanisms in mice are described in Science 299 (2003), 1196-201.  Mice lacking a neurotransmitter have difficulty to forget fearful experiences, Nature 421 (2003), 325-7.

Kanzi the bonobo has started to talk, NS (25 Jan., 2003), 12. Chimpanzee tool use is taught by group behaviour, Science 299 (2003), 27-8. Tests of a sonar designed to protect whales have been called of because the sonar itself might harm whales, Nature 421 (2003), 202.

 

Safety of Recombinant DNA Products

Recombinant human interleukin 11 reduces the frequency and load of bacteraemia in pateitns with homological malignant disease who are undergoing chemotherapy, Lancet 361 (2003), 275-80. Recombinant interferons have some effectiveness in reducing relapses in multiple sclerosis, Lancet 361 (2003), 545-52. Injection of recombinant activated factor VII can reduce perioperative blood loss and eliminate the need for blood transfusion in some patients, Lancet 361 (2003), 201-5. Interleukin 4 therapy may improve human autoimmune disease, NatMed. 9 (2003), 40-6.

On immunotherapy, SA (Feb. 2003), 12-3. A new drug delivery system containing cells producing proteins is being tested, NS (4 Jan., 2003), 18. Liver tissue has been converted into insulin producing cells, NS (1 Feb., 2003), 16. Misuse of prescribed stimulants is discussed in BMJ 326 (2003), 67.

 

Food safety

The debate over GM food is discussed in New Genetics and Society 21 (2002), 131-48; Issues in Science and Technology (Summer 2001), 31-6. On GM foods in Africa, Lancet 361 (2003), 500; NS (1 Feb., 2003), 4. In general on GM food, Newsweek (27 Jan. 2003), 40-45; NS (4 Jan., 2003), 3. In the US there are inquiries on whether some GM animals have entered the food chain, Nature 421 (2003), 682.

E. coli and food safety is discussed in Medico-Legal J. 69 (2002), 85. A call for evidence-based health claims for foods is in Science 299 (2003), 206-7. Benefits of food and mood are discussed in Agro-Food Industry Hi-Tech (Sept. 2002), 21-3.  Management of severely malnourished children is discussed in BMJ 326 (2003), 146-51.

The question of whether fast food is addictive is discussed in NS (1 Feb., 2003), 3, 26-9. The cost effectiveness of ways to lower the incidence of cardiovascular disease globally by 50% is reported in Lancet 361 (2003), 717-25. The risks of heart disease are not made worse by folate and vitamin B-12, BMJ 326 (2003), 131-4. Measures of lipids as indices of coronary risk is discussed in Lancet 361 (2003), 477-85, 777-80. On heart disease, NS (11 Jan., 2003), 36-9; NEJM 348 (2003), 639-41. Acrylamide in food is discussed in Lancet 361 (2003), 361-2.

Obesity is discussed in Science 299 (2003), 781, 846-60; BMJ 326 (2003), 229; Newsweek (27 Jan. 2003), 56; JAMA 289 (2003), 33-4, 76-9, 187-93, 229-30. Eating fish can reduce the risk of stroke, from even once a month, JAMA 289 (2003), 3130-6. Links between dairy food and Parkinson7s disease have been suggested, BMJ 326 (2003), 10. Food portions and sizes have increased in the USA since 1977, JAMA 289 (2003), 450-3. The safety of alcohol is discussed in SA (Feb. 2003), 62-9; NEJM 348 (2003), 109-18, 163-4; JAMA 289 (2003), 579-88. Arkansas has banned the sale of clean urine that is sold to beat drug testing, BMJ 326 (2003), 300.

 

Disease Risks & Drugs (see next issue for more)

A paper on the ethical issues is Dupont, BM., "The ethics of innovative medicine: From the possible to the permissible?", Biology International 43 (Dec. 2002), 11-6. Ethics of electroconvulsive therapy is discussed in Issues in Medical Ethics 11 (2003), 9-12. Taxomifen can reduce the risk of breast cancer, Lancet 361 (2003), 296-300.

The safety of marijuana and other drugs is discussed in JAMA 289 (2003), 427, 482-3. The WHO issued a revised draft of its Framework on Tobacco Control on 15 January 2003 that makes the demands softer and no longer includes a total advertising ban on cigarettes, Lancet 361 (2003), 315, 611-2. The cardiotoxicity of smoking appears not to be linked to apolipoprotein E genotype, Lancet 361 (2003), 396-8. On the dangers of cigarettes, Lancet 360 (2002), 1033-4.

 

Patenting & Business

Gene patents are discussed in J. Commercial Biotechnology 9 (2003), 135-42; The Pharmacogenomics  J. 2 (2002), 361-6. WTO and the access to drugs globally is discussed in Lancet 361 (2003), 269. The use of out-licensing of drugs is discussed in Lancet 361 (2003), 341-4. On value-based patents, Lancet 361 (2003), 613-4. The way industry alters opinion is discussed in GeneWatch 16 (Jan. 2003), 8-9.

Results of interviews and a survey of companies is in Kato, M. & Macer, DRJ. "How biotechnology companies respond to bioethical issues", J. Commercial Biotechnology 9 (2003), 153-62. A series of papers on the socio-economic issues of biotechnology are in New Genetics and Society 21 (August 2002), 101-248. Cuban biotech is discussed in J. Commercial Biotechnology 9 (2003), 147-52.

 

Birth Control

A book review of Evolution, Gender and Rape is NS (1 Feb., 2003), 46. Viagra is discussed in NS (25 Jan., 2003), 25. The threat to the environment may be more from the increasing number of households than persons, Nature 421 (2003), 489-90. Emergency contraception as over-the-counter medicine is discussed in NEJM 348 (2003), 82-3. A male pill is being developed, JAMA 289 (2003), 164. Debates over oral contraceptives are in BMJ 326 (2003), 254. A study of unplanned child bearing in Kenya is in SSM 56 (2003), 167-78.

The long-term effects of hormone replacement therapy (HRT) are discussed in Lancet 361 (2003), 253-5; JAMA 289 (2003), 44-5, 537-8; BMJ 326 (2003), 322-6; NEJM 348 (2003), 645-50.

 

Embryo Status

The legal representation of the embryo is discussed in Health Care Analysis 8 (2000), 171-88. Conditional attention and abortion is discussed in The Pelican Record 41 (Dec. 2002), 58-68. Japan has allowed use of dead fetuses for stem cell research, APBN 7 (2003), 13.

Assisted Reproductive Technology (ART)

Discussion of the claims of human cloning by Raelians is in BME 184 (Jan. 2003), 5; Science 299 (2003), 343-4; Associated Press (30 Jan. 2003); NS (11 Jan., 2003), 3, 8-11; Economist (4 Jan. 2003), 61-2. There is a dilemma for journals about publishing results of human cloning experiments, Nature 421 (2003), 199. US scientific panels and politics are discussed in NatMed. 9 (2003), 153. On cloning debates, see the journal Cloning. A two year process to gain approval for research on stem cells in Germany is reported in Science 299 (2003), 31. There can be different interpretations of the same results about the promise of stem cell research, Science 299 (2003), 324. On stem cell research, Bioethics 16(Nov. 2002), special issue; NatMed. 9 (2003), 156-7; Nature 421 (2003), 102; Science 299 (2003), 1009. Attempts to stop research on human-animal chimeras  have been made in the USA by legal means of patent protection, Nature 421 (2003), 4. The US House of representatives passed a law banning all types of cloning, Science 299 (2003), 799.

A Dutch study has found children born from IVF have a significantly higher risk of developing retinoblastoma, Lancet 361 (2003), 273-4, 309-10. On ART and the law, Medico-Legal J. 69 (2001), 13-24. The welfare of the child is discussed in Health Care Analysis 8 (2000), 27-34. There are papers on ART in Health Care Analysis 8 (2000), 1-154. Surrogacy is discussed in Health Care Analysis 8 (2000), 19-26, 101-7. Egg sharing is considered positive in results in F&S 79 (2003), 69-73. Lack of policy ion the USA on reducing multiple pregnancies from IVF is debated in F&S 79 (2003), 17-29.

The UK has decided to allow children born from donor sperm or eggs to know their genetic parents identity, BMJ 326 (2003), 240.  A Japanese committee has suggested the same conclusion to the government. On the UK ban on screening of embryos to inform parents about donor type, BMJ 326 (2003),  11.

     

Fetal Environment & Neonates

Consumption of folic acid does not appear to increase frequency of multiple births, Lancet 361 (2003),  380-4. Links between fetal growth and breast cancer are investigated in BMJ 326 (2003), 248-51. Sex ratio and fathers exposed to polychlorinated biphenyls are discussed in Lancet 360 (2002), 1887. Events in birth are the major cause of neonatal brain injury, Lancet 361 (2003), 713, 736-42. Effect of fetal sex on labour is discussed in BMJ 326 (2003), 137. Smoking and sex ratio is discussed in Lancet 360 (2002), 1514-5. Adverse effects of antiretroviral treatment in pregnancy are discussed in NEJM 348 (2003), 471-2.

A book review on Maternity care in Developing Countries is Lancet 360 (2002),  1894. How children can help in families, NS (7 Dec., 2002), 44-7. A Swedish study of what puts children of lone parents at risk is Lancet 361 (2003), 271, 289-95. Death of a child increases the risk of death in the parents also, Lancet 361 (2003), 363-7. Association between child sexual abuse and later abusive behaviour is reported in Lancet 361 (2003), 446, 471-6. Sexual orientation is discussed in NEJM 348 (2003), 571-2.

The marketing of infant formula is discussed in BMJ 326 (2003), 113-4, 127-30. Breast feeding has an analgesic effect, BMJ 326 (2003), 13-5.

Genetic Disease Markers

A review of polycystic disease is in Lancet 361 (2003), 774-6. A review of cystic fibrosis is Lancet 361 (2003), 681-9. Autism may not be caused by genes, GeneWatch 16 (Jan. 2003), 4-6.

A dominant SUR1 mutation causes autosomal dominant type 2 diabetes, Lancet 361 (2003),272, 301-7. Discussion of genes and schizophrenia is in Lancet 361 (2003), 417-9.

General discussion of the way genetic association studies are done is in Lancet 361 (2003), 357, 567-71. Telomeric shortening in adults over age is associated with earlier death and aging, Lancet 361 (2003), 393-5.

Genetic Screening Methodology

Detection of fetal DNA in maternal plasma is still difficult, Lancet 361 (2003), 193-4. The question of whether 35 years age is a cutoff for maternal plasma screening for Down syndrome is raised in Prenatal Diagnosis 22 (2002), 1195-200. Prenatal diagnosis of long QT syndrome is reported in Prenatal Diagnosis 22 (2002), 1209-12.

Genetic microarrays are discussed in JAMA 289 (2003), 155-61; NatMed. 9 (2003), 9; NatGen 32 (2002), Supplement, 461-552. Genetic tests can separate out tumours that are easy to be controlled by chemotherapy, or those which are likely to spread, NS (14 Dec., 2002), 19. On single cell expression profiling, Science 297 (2002), 836-40.

Population screening is reviewed in NEJM 348 (2003), 50-8. Adding a test for human papillomavirus to cervical cancer screening is suggested in NEJM 348 (2003), 48990.  On lung cancer screening, JAMA 289 (2003), 313+, 357-8. Prostrate cancer screening is common but not yet proven, Am J. Med. 113 (2002), 663-7. Ovarian cancer can be detected by SNP analysis, Lancet 360 (2002), 1667.

DNA Fingerprinting & Privacy

The British insurers and BMA joint statement on medical information and insurance is in BME 184 (Jan. 2003), 7-11; www.bma.org.uk and www.abi.org.uk. A study on privacy laws on insurer behaviour is Genetic Testing 4 (2000), 31-42. There is a lack of data on genetic discrimination, European J. Human Genetics 11 (2003), 1-2; Nature 421 (2003), 313.

The use of DNA fingerprinting to show convicted criminals may be innocent is discussed in GeneWatch 16 (Jan. 2003), 10-1. Use of DNA in forensic evidence in Australasia is in GeneWatch 16 (Jan. 2003), 12-3. In general, NatGen 33 (2003), 109-10. A study has found more than half the published genetic databases of mitochondrial DNA have mistakes, Nature 421 (2003), 773-4.

UNESCO is calling for comments on the Draft Revised Outline of the International Declaration on Human Genetic Data, at their web site. Genetic privacy is discussed in SSM 56 (2003), 53-65; Medicine, Health Care and Philosophy 1 (1998), 225-33. Genetics studies in Iceland suggest similar diversity to the rest of Europe, Nature 421 (2003), 678. On tracing genetic identity, BMJ 325 (2002), 1469-71.

Use of DNA tests for microbial disease monitoring is discussed in Science 299 (2003), 1164-5.

Ethics & Genetic Screening

A discussion of genetic testing is in Bennet, T., "Fundamental problems and solutions concerning genetic testing", Alpha Omega 5(2), 337-362. There are also papers on medical genetics in New Genetics and Society 21 (2002), 261-302, 327-50; Medicine, Healthcare and Philosophy 1 (1998), 207-8. A survey of the use of informed consent forms in genetic counseling is J. Genetic Counseling 10 (2001), 3-24. A paper on informed consent in pharmacogenomics is in The Pharmacogenomics  J. 2 (2002), 343. A series of papers on population screening for hemochromatosis is Genetic Testing 4 (2000), 95-232. Risk perceptions of participants in familial hypercholesterolemia screening are reported in AJMG 116A (2003), 136-43.

Genetic technology as a threat to deafness is discussed in Medicine, Healthcare and Philosophy 1 (1998), 209-15. Prenatal diagnosis for deafness is possible, J. Genetic Counseling 10 (2001), 121-31. Ethics of cochlear implants are discussed in Theoretical Medicine 22 (2001), 337-49.  The preferences of women for prenatal diagnosis are discussed in Genetic Testing 4 (2000), 23-32. Breast cancer screening is discussed in J. Genetic Counseling 10 (2001), 185+, 215-32; Genetic Testing 4 (2000), 43+, 265-72. Reasons for declining cancer genetic counseling are described in J. Genetic Counseling 10 (2001), 25+. The Jewish carrier screening panel is discussed in Genetic Testing 5 (2001), 83-5. On carrier screening for cystic fibrosis, Genetic Testing 5 (2001), 111+. Disclosure of Huntington's Disease to family members is reviewed in BMJ 326 (2003), 331-3; Genetic Testing 4 (2000), 359-64.

A study of focus groups of professional challenges of patients with genetic concerns is J. Genetic Counseling 10 (2001), 97+. On genetics and public health, JAMA 289(2003), 99-100. Attitudes towards enrolment of children in genetic susceptibility research in the USA is reported in AJMG 116A (2003), 117-28, 315-23.

A discussion of the compulsory health screen before marriage in China is Hesketh, T. "Getting married in China: Pass the medical first", BMJ 326 (2003), 277-9. Book reviews of Genetic Politics are in Lancet 361 (2003), 267. Geneticisation of medicine is discussed in Medicine, Healthcare and Philosophy 1 (1998), 235-43; 4 (2001), 19-30, 37-46. Eugenics is discussed in Nature 421 (2003), 213-4; AJPH 93 (2003), 11; Medicine, Healthcare and Philosophy 4 (2001), 1-3, 5-17. Recent trends in disability in USA are discussed in JAMA 288(2002), 3137-46. The benefits of general intelligence are discussed in  Science 299 (2003), 192-3. The search for genes for longevity is reviewed in Nature 421 (2003), 789-90.

The commercialisation of home genetic test kits is discussed in JAMA 289(2003), 45-6; NatMed. 9 (2003), 147;  J. Biolaw & Biobusiness 3 (1999), 29-39; Medicine, Healthcare and Philosophy 1 (1998), 217-24. OECD and genetic testing is discussed in J. Biolaw and Biobusiness 4 (2001), 34-6.

Gene Therapy

   The possible extension of lifespan in humans is discussed in Population and Development Review 27 (2001), 411+. Medicine and aesthetics are discussed in Medicine, Health Care and Philosophy 2 (1999), 115-187. On regulation of gene therapy in the UK, Human Gene Therapy 12 (2001), 711-20.

   The cases of leukemia in two children in France who are gene therapy participants with SCID have raised safety questions that have lead to stopping trials like that in the USA, Nature 421 (2003), 305, 595, 678; Science 299 (2003), 320, 495, 991; NS (25 Jan., 2003), 12; NEJM 348 (2003), 255-6; BMJ 326 (2003), 181. Stem cell transplants as treatment options for SCID and other immunodeficiency diseases are discussed in Lancet 361 (2003), 541-2, 553-60.

   The promise of gene therapy is discussed in Human Gene Therapy 12 (2001), 1483-4. The need to restore public trust in gene therapy is made in J. BioLaw and Business (2001), 3-4. On gene therapy for HIV, Human Gene Therapy 12 (2001), 1013-9. Use of nonviral vectors is reviewed in Human Gene Therapy 12 (2001), 861-70.

Human Genome Project (HGP)

Personal genome sequencing is discussed in HCR 33 (Jan. 2003), 9. General articles celebrating the 50 years of history since the publication of the paper on DNA structure  are in Lancet 361 (2003), 580-1. On the future of the HGP, Science 298 (2002), 1694-5. On the ignificance of the human geome, a letter from Venter is in Science 299 (2003), 1183-4.

The genome of sea squirt has been sequenced.  On the mouse genome, NatGen 33 (2003), 3-4. The ring-like structure of Deinococcus radiodurans genome may be the reason for its radioresistance, Science 299 (2003), 254-9. The involvement of southern genome research centres in sequencing projects is applauded in Science 298 (2002), 2298-9. The question of whether Dr. Craig Venter and colleagues can make a new genome from scratch is discussed,Science 299 (2003), 1006-7.

Pharmacogenetics is discussed in NEJM 348 (2003), 529-49, 553-6. On the genetic structure of human populations, Science 298 (2002), 2342-3, 2381-4; SA (Feb. 2003), 22-3. The genetic origins of Andaman Islanders are described in AJHG 72 (2003), 178-84. Neanderthals are discussed in NS (11 Jan., 2003), 46.

General Medical Ethics (see next issue for more)

Discussion of the behaviourome project of Darryl Macer is in Discover 24 (March 2003), 12. Empirical studies in bioethics are reviewed in BME 184 (Jan. 2003), 13-24.

Violence and mental health is discussed in Issues in Medical Ethics 11 (2003), 13-6. A review of emotions and fear is Discover 24 (March 2003), 32-9. Discussion of doctors treating persons associated with them in personal relationships is discussed in Lancet 361 (2003), 440.

   A paper on China is Dring, O. " Science and society: China's struggle for practical regulations in medical ethics",  Nature Reviews Genetics 4 (2003), 233-9.

The description in the Book of Daniel in the Bible of a clinical trial is discussed in NEJM 348 (2003), 83.

Law & Medical Ethics

A series of papers on health and human rights are in JLME 30 (4), 510-754.  Papers range from issues of HIV to those of patents. The ethics of conducting clinical trials between Europeans and poorer nations is discussed in Lancet 361 (2003), 579. On the role of IRBs, Bioethics Forum 16(4), (2000), 31-6. Letters on the Cincinnati radiation tests are in JAMA 289 (2003), 301-2.

A US Federal Court of Appeals in St. Louis has ruled that a patient with mental disease who is on death row can be treated with drugs to make him competent so that he can be executed for a 1979 murder conviction, Lancet 361 (2003), 621. A debate on the role of Israeli doctors in torture is in Lancet 361 (2003), 424-6. On the role of medical experts in courts, BMJ 326 (2003), 294-5.

Medical errors stem from the system not just individuals, BMJ 326 (2003), 300. On medical errors, Nursing Times (21 Jan. 2003), 22-5; Bioethics Forum 16(4), (2000), 23-30. The risk factors for retained sponges and instruments after surgery are reviewed in NEJM 348 (2003), 229-35.

Scientific Ethics

Papers on cheating in academia are in Ethics and Behavior 11 (2001), 217-361. Making information openly available is called for in Science 299 (2003), 990. Redundant publications are common, Nature 421 (2003), 209. Multiple authorship is discussed in JAMA 288 (2002), 3166-7. Peer review may not increase the quality of publications, BMJ 326 (2003), 241. Plagiarism in India is discussed in Science 299 (2003), 800. Misconduct cases are discussed in  Nature 421 (2003), 681. Financial conflicts of interest are discussed in JAMA 289 (2003), 454-65.

Scientists have been asked to self-censor sensitive data that could make bioweapons, Science 299 (2003), 321, 1149; Nature 421 (2003), 197. On the balance between freedom and terrorism, NS (18 Jan., 2003), 3; Science 299 (2003), 1175; Nature 421 (2003), 785. Arguments against scientific boycotts are made in Nature 421 (2003), 314.

 

Euthanasia & Terminal Care

Euthanasia is discussed in HCR 33 (Jan. 2003), 17-9; JAMA 289 (2003), 233-4. Advance directives require good communication, JAMA 289 (2003), 96. Euthanasia in Switzerland by non-medical staff is discussed in BMJ 326 (2003), 271-3. Tourism for end of life treatment is discussed in BMJ 326 (2003), 242. The Dutch supreme court has said that being tired of life is not grounds for euthanasia, BMJ 326 (2003), 71.

Spirituality at the end of life is discussed in J. Palliative Medicine 4 (2001), 333-5. Japanese religion and the end of life is discussed in AIBA Newslink 6 (Feb. 2003), 1-3. Chinese perspectives on the meaning of death are discussed in Death Studies 26 (2002), 143-75. Death anxiety in Chinese students is reported in Death Studies 26 (2002), 491-9. A study of UK physicians attitudes to euthanasia is in Death Studies 26 (2002), 479-90; see also BMJ 326 (2003), 30-4. Death in East African cultures is reviewed in J. Hospice and Palliative Nursing 3 (2001), 59-61; and in Hispanic culture, pp. 29-33. Study of end of life in different cultures is reported in Death Studies 26 (2002), 567-92; BMJ 326 (2003), 228. Also on dying, JAMA 289 (2003), 235-6. Comparisons of happiness across culture is made in SA (Feb. 2003), 17.

Palliative care in New Zealand is reviewed in J. Palliative Medicine 4 (2001), 70-4.Conflicts at the end of life are discussed in J. Palliative Medicine 4 (2001), 1-3. Telemedicine and end of life care is discussed in J. Clinical Ethics 12 (2001), 64-79.

Organ Transplants & Brain Death

A paper on how to deal with dead bodies is Pentz, RD. et al. "Revisiting ethical guidelines for research with terminal wean and brain-dead participants", HCR 33 (Jan. 2003), 20-6, 3-4; Science 299 (2003), 29-30; BMJ 325 (2002), 648-51. A further paper on body value is in HCR 33 (Jan. 2003), 27-33. Papers on regulating body parts are in Health Care Analysis 8 (2000), 83-201. A study of 19th century body sales is NEJM 347 (2002), 952. A study of grief and post mortems is Death Studies 26 (2002), 837-49; also see BMJ 325 (2002), 1121. A review of plastic body parts is Science 298 (2002), 828-9; and an anatomy display, JAMA 288 (2002), 2525-9. Ethics of face transplants are discussed in Nature 420 (2002), 449.

Radiological diagnosis of brain death is described in JAMA 288 (2002), 2121. On brain death, BMJ 325 (2002), 598-9; Lancet 360 (2002), 425-6. A book review on The Vegetative State is JAMA 289 (2003), 101-2; also NEJM 347 (2002), 1386-7. Kidney transplants from heart-dead donors are reviewed in NEJM 347 (2002), 281-3, 1799-800.

A review is Burgio, GR. Et al. "Ethical reappraisal of 15 years of cord-blood transplantation", Lancet 361 (2003), 250-2. Guidelines on organ donations from San Thomas Hospital in the Philippines are in Southeast Asian Center for Bioethics Bioethics Newsletter 15 (Jan. 2003), 1-3. The concept of autonomy and living organ donors are discussed in Theoretical Medicine 22 (2001), 351-68. A liver has been treated with radiotherapy outside of the body and returned in Italy to remove cancer, NS (21 Dec., 2002), 7. On organ transplants in HIV infected persons, NEJM 347 (2002), 1801-3.

Israel is considering paying organ donors, BMJ 326 (2003), 126.  A review of the economic consequences of selling a kidney in India is JAMA 288 (2002), 1589-93. Organ trafficking in Punjab has been disclosed, BMJ 326 (2003), 180. On selling organs, BMJ 325 (2002), 510, 795, 835-6; Lancet 360 (2002), 948-9; NEJM 347 (2002), 1382-4. Equity of stem cell transplants and organ growth is discussed in NS (19 Oct., 2002), 27.

Xenotransplantation is discussed in Medicine, Health care and Philosophy 4 (2001), 53-70; Nature 418 (2003), 811, 909; 419 (2002), 5; NatMed. 8 (2002), 1047. Cross-species retroviral transmission from macaques to humans is reported in Lancet 360 (2002), 387-8. Implantable chips are discussed in SA (Jan. 2003), 10-1.

Replacement organs are discussed in NS (4 Jan. 2003), 19; (25 Jan., 2003), 16. Fetal retinal cells may be able to rejuvenate retinas and restore sight, NS (1 Feb., 2003), 14-5. On artificial eyes, NS (23 Nov., 2002), 35-7. Growing personal body parts in a dish is described in NS (14 Sept., 2003), 14. Tissue scaffolds are described in J. Artificial Organs 5 (2002), 77-83. Robots may be hard to distinguish, SA (Oct. 2002), 24-31. Stem cells to repair the heart are discussed in Circulation Research 91 (2002), 1092-1102; 92 (2003), 6-8; Lancet 361 (2003), 11-2. The status of artifical heart research is reviewed in J. Artificial Organs 5 (2002), 147-8, 149-55.  Animal experiments are discussed in Science 298 (2002), 2141-2. Diseased brains attempt to repair themselves, NS (8 Feb., 2003), 23. Pancreatic islet transplants are discussed in Lancet 360 (2002), 1999-2000. Early kidney precursors are new sources for transplants, NatMed. 9 (2003), 53-60.

Health Costs

Papers on health equity in several countries are presented in Health Policy and  Planning 17 Supplement Dec. 2002, 1-84; and inequity in the poor in Tanzania in  Lancet 361 (2003), 540-1, 561-6. Gender bias in medical studies is discussed in JAMA 289 (2003), 397-400. Racial and ethnic biases are discussed in SSM 55 (2002), 2017-31; AJPH 92 (2002), 1895-9; 93 (2003), 189, 191-208, 277-84; JAMA 289 (2003), 360. Employment discrimination and health is discussed in AJPH 93 (2003), 226-31.

Managed care ethics is discussed in HCR 33 (Jan. 2003), 34-42. Review of HMOs decisions on medical necessity is reported in NEJM 347 (2002), 2178-82. In the Netherlands a widespread health insurance fraud has been discussed, Lancet 361 (2003), 583. An embargo against Haiti is discussed in Lancet 361 (2003), 420-2. On solidarity in health care, Health Care Analysis 8 (2000), 329-411. Solidarity in Tanzania is discussed in SSM 56 (2003), 1929-46. No fault medical injury compensation in New Zealand is discussed in BMJ 326 (2003), 79-80.

The new leadership of WHO under a Korean Dr. Jong-Wook Lee is discussed in Lancet 361 (2003),  194, 231-8, 253, 399-403. Also on WHO, BMJ 326 (2003), 122-5. The UN plans for health of Iraqi people in the event of war are discussed in Lancet 361 (2003), 345, 493, 622-31. Health in Uganda is discussed in Lancet 361 (2003), 319; Vietnam, SSM 56 (2003), 333-42; and in Russia in Lancet 361 (2003), 498. Comparisons of the health care systems in several countries are in AJPH 93 (2003), 20-61; and in USA, AJPH 93 (2003), 14-9, 75-85, 92-129 193; JAMA 289 (2003), 305-12, 354-6. Japan is reducing its international aid, Lancet 361 (2003), 406.

Internet Sites Discussion of donating books and journals to less developed countries is in BMJ 326 (2003), 298. Openness of papers is important, BMJ 325 (2002), 456. Biosafety files are available from the Netherlands, Biotechnology and Development Monitor 49 (March 2002), 13. Use of Internet for conferences is discussed in Biotechnology and Development Monitor 49 (March 2002), 7-9.

A consumer health report card on the Internet is discussed in JAMA 287 (2002), 1277-87; BMJ 325 (2002), 555-6. Quality on the Internet is discussed in BMJ 325 (2002), 557-8.  Regulation of helath information is more difficult, BMJ 325 (2002), 602-6.

GenInfo a bimonthly electronic newsletter concentrating on new policy  statements on human genetics from international, regional and national sources is online at  www.humgen.umontreal.ca/en/GenInfo.cfm

Prepared by Darryl Macer
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